Prolotherapy
Injection of an irritant solution (usually hypertonic dextrose) into joints, ligaments, or tendons to trigger a localized healing response, marketed for chronic joint pain, ligament laxity, and 'regenerative' joint support.
Evidence
Systematic reviews show dextrose prolotherapy reduces pain and improves function in knee osteoarthritis, but trials are small and non-standardized, and there is no evidence for any systemic longevity benefit.
Regulatory notes
- European Union
- Uses approved dextrose solutions off-label as a physician-administered procedure; not a licensed longevity treatment and claims must stay within musculoskeletal scope.
- United States
- Not FDA-approved as a specific therapy; performed off-label with standard injectable dextrose and marketed at physician discretion.
- United Arab Emirates
- Offered by licensed practitioners as an orthopedic/pain procedure under DHA oversight; longevity claims are not endorsed.
- United Kingdom
- Available as an off-label physician-administered injection; no approved longevity indication.
General information, not medical or legal advice. See our disclaimer.
Also known as
prolotherapy, dextrose prolotherapy, hypertonic dextrose injection, regenerative injection therapy, RIT, proliferation therapy, sugar injection
Where to find it
75 clinics in the directory offer prolotherapy. Prices shown are the cheapest for this treatment where published; always confirm with the venue.
London
- Eskulap Clinicfrom GBP 200
- London Bridge Regenerative Clinicfrom GBP 250
- Mayfair Practicefrom GBP 250
- Clinicbefrom GBP 275
- Proback Clinic Victoriafrom GBP 275
- ProHealth Clinicfrom GBP 285
- HUM2N Longevity Clinicfrom GBP 290
- Zen Healthcare Hampsteadfrom GBP 400
- PRP London Clinicfrom GBP 450
- Rejuvence Clinicfrom GBP 450
- Hampstead Aestheticsfrom GBP 500
- Optimise Healthfrom GBP 550
- Harley Street Medicsfrom GBP 599
- Reborne Longevity Londonfrom GBP 600
- Omniya Clinicfrom GBP 650
- Geneviv Clinicfrom GBP 700
- London Natural Therapiesfrom GBP 850
- Este Medical Groupfrom GBP 1,500
- Menon Healthfrom GBP 1,500
- Drip Hydration London Mobile IV Therapyfrom USD 1,999
- 111 Harley Streetfrom GBP 6,500
- 111CRYO at Harvey Nichols
- Aestha Clinic
- Athlete Lab UK
- BelleCell
- BXR London (The Lab)
- Chelsea Pharmacy Medical Clinic
- Cloud Twelve
- Cortisone London / Harley Street Joint Care
- Dr Monica Lascar
- Dr SNA Clinic
- Dr Stavy Nikitopoulou
- Dr SW Clinics
- Dr Theodora Mantzourani (London Functional Clinic)
- Effect Doctors
- EGA Clinic (London Longevity Hub)
- Harley Street Longevity Club
- Harley Street Specialist Hospital
- Harpal Clinic
- HOOKE
- HOOKE Fitness
- King Edward VII's Hospital
- Lanserhof at The Arts Club
- Levitas Clinic London
- Liv Harley Street Hospital IV Drip & Vitamin Infusion Clinic
- London Bridge Sports Medicine (LBSM)
- London Centre for Functional Medicine
- London Centre for Functional Medicine
- London Hormone Clinic
- London Oxygen Centre
- London Regenerative Institute (LRI)
- Longevity Centre
- Marylebone Diagnostic Centre
- Mayo Clinic Healthcare London
- Menopause Care
- Miller Health
- Neil Livemore Consulting
- Omnia Lifestyle
- One5 Health
- OneTrack Club
- Remedi London
- Solice Health
- Stemvita
- Surrenne
- Sutherland House
- The Body Lab
- The Bvlgari Spa (Recovery Suite)
- The Clinic Holland Park
- The Forbes Clinic of Integrative Medicine
- The Hale Clinic
- The Harley Street Hospital
- The Longevity Doctor
- The Regenerative Clinic
- The Sleep Disorders Clinic
- Third Space Recovery Spa