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Bioidentical Hormone Replacement Therapy (BHRT)

Hormone therapy using compounds marketed as chemically identical to endogenous hormones, often as custom-compounded pellets, creams, or troches dosed via saliva or blood testing.

Hormone therapy using compounds marketed as chemically identical to endogenous hormones, often as custom-compounded pellets, creams, or troches dosed via saliva or blood testing. Heavily promoted by wellness and anti-aging clinics as a natural, personalized alternative to conventional HRT.

Evidence

emerging

FDA-approved bioidentical formulations work like standard HRT, but custom-compounded BHRT and saliva-guided dosing lack rigorous evidence, and the anti-aging/longevity positioning is unproven and flagged as potentially misleading by regulators.

Regulatory notes

European Union
Compounded/bioidentical hormones fall outside standard EMA marketing authorization and are prescription-only; Spanish authorities treat compounded formulas as pharmacy-prepared prescriptions, not licensed products.
United States
Compounded BHRT is not FDA-approved; the FDA and a 2020 NASEM report warn against routine compounded use and marketing claims, though the underlying hormones are prescription-only.
United Arab Emirates
Compounded hormone products are prescription-only and require DHA/DoH-licensed prescribing; unregistered compounded formulations face restrictions under MoHAP rules.
United Kingdom
Compounded BHRT is not a licensed medicine; prescription-only and not recommended over regulated HRT by UK menopause guidance.

General information, not medical or legal advice. See our disclaimer.

Also known as

BHRT, bioidentical hormones, compounded hormone therapy, cBHT, bioidentical HRT, pellet therapy, hormone pellets, BioTE

Where to find it

33 clinics in the directory offer bioidentical hormone replacement therapy (bhrt). Prices shown are the cheapest for this treatment where published; always confirm with the venue.

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